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KMID : 0377619640060010059
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Korean Jungang Medical Journal
1964 Volume.6 No. 1 p.59 ~ p.61
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Effect of Cortisone on the Glutamin-pyruvic Transaminase Activity in the Subcellular Fractions of Rat Liver
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Abstract
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The authors have studied the subcellar distrubution of glutamic- pyruvic transaminase (GPT) activities in the normal and cortisone treated rat liver.The GPT activities in each fraction increased in the cortisone treated group.
According to the autors´ result the relative increment of the GPT activitity in the mitochomdrial fraction compare to that of in other fractions was not remarkable. The possible interpretation of this resrult was such that the effect of cortisone on mitochondrial fraction was less than on the other fractions, the reactien. alanine+α-glutamic acid-pyruvic acid+ glutamic acid was less active in this fraction.
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